MITF has a central role in regulating starvation-induced autophagy in melanoma

The MITF transcription factor is a master regulator of melanocyte development and a critical factor in melanomagenesis. The related transcription factors TFEB and TFE3 regulate lysosomal activity and autophagy processes known to be important in melanoma. Here we show that MITF binds the CLEAR-box el...

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Detalles Bibliográficos
Autores principales: Möller, Katrin, Sigurbjornsdottir, Sara, Arnthorsson, Asgeir O., Pogenberg, Vivian, Dilshat, Ramile, Fock, Valerie, Brynjolfsdottir, Solveig H., Bindesboll, Christian, Bessadottir, Margret, Ogmundsdottir, Helga M., Simonsen, Anne, Larue, Lionel, Wilmanns, Matthias, Thorsson, Vesteinn, Steingrimsson, Eirikur, Ogmundsdottir, Margret H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355916/
https://www.ncbi.nlm.nih.gov/pubmed/30705290
http://dx.doi.org/10.1038/s41598-018-37522-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355916/
https://www.ncbi.nlm.nih.gov/pubmed/30705290
http://dx.doi.org/10.1038/s41598-018-37522-6

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