Genetic regulatory mechanisms in human osteoclasts suggest a role for the STMP1 and DCSTAMP genes in Paget’s disease of bone

Paget’s disease of bone (PDB) is characterised by focal abnormalities of bone remodelling, with increased osteoclastic resorption the primary feature of the disease. Genetic factors have been shown to play an important role in PDB, and genome-wide association studies (GWAS) have identified 7 genetic...

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Detalles Bibliográficos
Autores principales: Mullin, Benjamin H., Zhu, Kun, Brown, Suzanne J., Mullin, Shelby, Tickner, Jennifer, Pavlos, Nathan J., Dudbridge, Frank, Xu, Jiake, Walsh, John P., Wilson, Scott G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355970/
https://www.ncbi.nlm.nih.gov/pubmed/30705363
http://dx.doi.org/10.1038/s41598-018-37609-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355970/
https://www.ncbi.nlm.nih.gov/pubmed/30705363
http://dx.doi.org/10.1038/s41598-018-37609-0

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