Cargando…
Genetic regulatory mechanisms in human osteoclasts suggest a role for the STMP1 and DCSTAMP genes in Paget’s disease of bone
Paget’s disease of bone (PDB) is characterised by focal abnormalities of bone remodelling, with increased osteoclastic resorption the primary feature of the disease. Genetic factors have been shown to play an important role in PDB, and genome-wide association studies (GWAS) have identified 7 genetic...
Autores principales: | Mullin, Benjamin H., Zhu, Kun, Brown, Suzanne J., Mullin, Shelby, Tickner, Jennifer, Pavlos, Nathan J., Dudbridge, Frank, Xu, Jiake, Walsh, John P., Wilson, Scott G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355970/ https://www.ncbi.nlm.nih.gov/pubmed/30705363 http://dx.doi.org/10.1038/s41598-018-37609-0 |
Ejemplares similares
-
Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts
por: Mullin, Benjamin H., et al.
Publicado: (2020) -
Targeted sequencing of DCSTAMP in familial Paget's disease of bone
por: Sultana, M.A., et al.
Publicado: (2019) -
Leveraging osteoclast genetic regulatory data to identify genes with a role in osteoarthritis
por: Mullin, Benjamin H, et al.
Publicado: (2023) -
STMP-Net: A Spatiotemporal Prediction Network Integrating Motion Perception
por: Chen, Suting, et al.
Publicado: (2023) -
Alternative splicing in osteoclasts and Paget’s disease of bone
por: Klinck, Roscoe, et al.
Publicado: (2014)