Disease‐associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria

Accumulation of the protein tau characterises Alzheimer's disease and other tauopathies, including familial forms of frontotemporal dementia (FTD) that carry pathogenic tau mutations. Another hallmark feature of these diseases is the accumulation of dysfunctional mitochondria. Although disease‐...

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Detalles Bibliográficos
Autores principales: Cummins, Nadia, Tweedie, Andrea, Zuryn, Steven, Bertran‐Gonzalez, Jesus, Götz, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356067/
https://www.ncbi.nlm.nih.gov/pubmed/30538104
http://dx.doi.org/10.15252/embj.201899360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356067/
https://www.ncbi.nlm.nih.gov/pubmed/30538104
http://dx.doi.org/10.15252/embj.201899360

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