Cargando…

Hypoxia affects Slc7a5 expression through HIF‐2α in differentiated neuronal cells

An imbalance of branched‐chain amino acids (BCAAs) in the brain may result in neuropathological conditions, such as autism spectrum disorders. The L‐type amino acid transporter 1 (LAT1), encoded by the solute carrier transporter 7a5 (Slc7a5) gene, is critical for maintaining normal levels of BCAAs i...

Descripción completa

Detalles Bibliográficos
Autores principales: Onishi, Yuki, Hiraiwa, Manami, Kamada, Hikari, Iezaki, Takashi, Yamada, Takanori, Kaneda, Katsuyuki, Hinoi, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356171/
https://www.ncbi.nlm.nih.gov/pubmed/30761250
http://dx.doi.org/10.1002/2211-5463.12559