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Hypoxia affects Slc7a5 expression through HIF‐2α in differentiated neuronal cells
An imbalance of branched‐chain amino acids (BCAAs) in the brain may result in neuropathological conditions, such as autism spectrum disorders. The L‐type amino acid transporter 1 (LAT1), encoded by the solute carrier transporter 7a5 (Slc7a5) gene, is critical for maintaining normal levels of BCAAs i...
Autores principales: | Onishi, Yuki, Hiraiwa, Manami, Kamada, Hikari, Iezaki, Takashi, Yamada, Takanori, Kaneda, Katsuyuki, Hinoi, Eiichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356171/ https://www.ncbi.nlm.nih.gov/pubmed/30761250 http://dx.doi.org/10.1002/2211-5463.12559 |
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