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Plasmodium palmitoylation machinery engineered in E. coli for high‐throughput screening of palmitoyl acyl‐transferase inhibitors

Lipid‐based palmitoylation is a post‐translation modification (PTM) which acts as a biological rheostat in life cycle progression of a deadly human malaria parasite, Plasmodium falciparum. P. falciparum palmitoylation is catalyzed by 12 putative palmitoyl acyl‐transferase enzymes containing the cons...

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Detalles Bibliográficos
Autores principales: Yadav, Preeti, Ayana, R, Garg, Swati, Jain, Ravi, Sah, Raj, Joshi, Nishant, Pati, Soumya, Singh, Shailja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356172/
https://www.ncbi.nlm.nih.gov/pubmed/30761251
http://dx.doi.org/10.1002/2211-5463.12564