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NUP214 in Leukemia: It’s More than Transport

NUP214 is a component of the nuclear pore complex (NPC) with a key role in protein and mRNA nuclear export. Chromosomal translocations involving the NUP214 locus are recurrent in acute leukemia and frequently fuse the C-terminal region of NUP214 with SET and DEK, two chromatin remodeling proteins wi...

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Detalles Bibliográficos
Autores principales: Mendes, Adélia, Fahrenkrog, Birthe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356203/
https://www.ncbi.nlm.nih.gov/pubmed/30669574
http://dx.doi.org/10.3390/cells8010076