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The Capacity of Long-Term In Vitro Proliferation of Acute Myeloid Leukemia Cells Supported Only by Exogenous Cytokines Is Associated with a Patient Subset with Adverse Outcome

Acute myeloid leukemia (AML) is an aggressive malignancy, which is highly heterogeneous with regard to chemosensitivity and biological features. The AML cell population is organized in a hierarchy that is reflected in the in vitro growth characteristics, with only a minority of cells being able to p...

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Detalles Bibliográficos
Autores principales: Brenner, Annette K., Aasebø, Elise, Hernandez-Valladares, Maria, Selheim, Frode, Berven, Frode, Grønningsæter, Ida-Sofie, Bartaula-Brevik, Sushma, Bruserud, Øystein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356272/
https://www.ncbi.nlm.nih.gov/pubmed/30634713
http://dx.doi.org/10.3390/cancers11010073