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Aberrant hiPSCs-Derived from Human Keratinocytes Differentiates into 3D Retinal Organoids that Acquire Mature Photoreceptors

Human induced pluripotent stem cell (hiPSC)-derived three-dimensional retinal organoids are a new platform for studying the organoidogenesis. However, recurrent genomic aberration, acquired during generation of hiPSCs, limit its biomedical application and/or aberrant hiPSCs has not been evaluated fo...

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Detalles Bibliográficos
Autores principales: Shrestha, Rupendra, Wen, Yao-Tseng, Ding, Dah-Ching, Tsai, Rong-Kung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356277/
https://www.ncbi.nlm.nih.gov/pubmed/30634512
http://dx.doi.org/10.3390/cells8010036