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TALEN-Mediated Gene Targeting for Cystic Fibrosis-Gene Therapy

Cystic fibrosis (CF) is an inherited monogenic disorder, amenable to gene-based therapies. Because CF lung disease is currently the major cause of mortality and morbidity, and the lung airway is readily accessible to gene delivery, the major CF gene therapy effort at present is directed to the lung....

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Detalles Bibliográficos
Autores principales: Xia, Emily, Zhang, Yiqian, Cao, Huibi, Li, Jun, Duan, Rongqi, Hu, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356284/
https://www.ncbi.nlm.nih.gov/pubmed/30641980
http://dx.doi.org/10.3390/genes10010039