RAC1B: A Rho GTPase with Versatile Functions in Malignant Transformation and Tumor Progression

RAC1B is an alternatively spliced isoform of the monomeric GTPase RAC1. It differs from RAC1 by a 19 amino acid in frame insertion, termed exon 3b, resulting in an accelerated GDP/GTP-exchange and an impaired GTP-hydrolysis. Although RAC1B has been ascribed several protumorigenic functions such as c...

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Detalles Bibliográficos
Autores principales: Melzer, Catharina, Hass, Ralf, Lehnert, Hendrik, Ungefroren, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356296/
https://www.ncbi.nlm.nih.gov/pubmed/30621237
http://dx.doi.org/10.3390/cells8010021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356296/
https://www.ncbi.nlm.nih.gov/pubmed/30621237
http://dx.doi.org/10.3390/cells8010021

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