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Varlitinib Downregulates HER/ERK Signaling and Induces Apoptosis in Triple Negative Breast Cancer Cells

Triple-negative breast cancer (TNBC) is a complex disease associated with the aggressive phenotype and poor prognosis. TNBC harbors heterogeneous molecular subtypes with no approved specific targeted therapy. It has been reported that HER receptors are overexpressed in breast cancer including TNBC....

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Detalles Bibliográficos
Autores principales: Liu, Chun-Yu, Chu, Pei-Yi, Huang, Chun-Teng, Chen, Ji-Lin, Yang, Hsiu-Ping, Wang, Wan-Lun, Lau, Ka-Yi, Lee, Chia-Han, Lan, Tien-Yun, Huang, Tzu-Ting, Lin, Po-Han, Dai, Ming-Shen, Tseng, Ling-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356324/
https://www.ncbi.nlm.nih.gov/pubmed/30658422
http://dx.doi.org/10.3390/cancers11010105