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The Opposing Contribution of SMS1 and SMS2 to Glioma Progression and Their Value in the Therapeutic Response to 2OHOA

Background: 2-Hydroxyoleic acid (2OHOA) is particularly active against glioblastoma multiforme (GBM) and successfully finished a phase I/IIA trial in patients with glioma and other advanced solid tumors. However, its mechanism of action is not fully known. Methods: The relationship between SMS1 and...

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Detalles Bibliográficos
Autores principales: Fernández-García, Paula, Rosselló, Catalina A., Rodríguez-Lorca, Raquel, Beteta-Göbel, Roberto, Fernández-Díaz, Javier, Lladó, Victoria, Busquets, Xavier, Escribá, Pablo V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356341/
https://www.ncbi.nlm.nih.gov/pubmed/30646599
http://dx.doi.org/10.3390/cancers11010088