Mifepristone Overcomes Tumor Resistance to Temozolomide Associated with DNA Damage Repair and Apoptosis in an Orthotopic Model of Glioblastoma

The standard treatment for glioblastoma multiforme (GBM) is surgery followed by chemo/radiotherapy. A major limitation on patient improvement is the high resistance of tumors to drug treatment, likely responsible for their subsequent recurrence and rapid progression. Therefore, alternatives to the s...

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Detalles Bibliográficos
Autores principales: Llaguno-Munive, Monserrat, Romero-Piña, Mario, Serrano-Bello, Janeth, Medina, Luis A., Uribe-Uribe, Norma, Salazar, Ana Maria, Rodríguez-Dorantes, Mauricio, Garcia-Lopez, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356343/
https://www.ncbi.nlm.nih.gov/pubmed/30583528
http://dx.doi.org/10.3390/cancers11010016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356343/
https://www.ncbi.nlm.nih.gov/pubmed/30583528
http://dx.doi.org/10.3390/cancers11010016

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