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n-6 Linoleic Acid Induces Epigenetics Alterations Associated with Colonic Inflammation and Cancer

The farnesoid-X-receptor (FXR) protects against inflammation and cancer of the colon through maintenance of intestinal bile acid (BA) homeostasis. Conversely, higher levels of BA and cyclooxygenase-2 (COX-2) are risk factors for inflammation and cancer of the colon. In the United States, n-6 linolei...

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Detalles Bibliográficos
Autores principales: Romagnolo, Donato F., Donovan, Micah G., Doetschman, Tom C., Selmin, Ornella I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356359/
https://www.ncbi.nlm.nih.gov/pubmed/30650553
http://dx.doi.org/10.3390/nu11010171