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n-6 Linoleic Acid Induces Epigenetics Alterations Associated with Colonic Inflammation and Cancer
The farnesoid-X-receptor (FXR) protects against inflammation and cancer of the colon through maintenance of intestinal bile acid (BA) homeostasis. Conversely, higher levels of BA and cyclooxygenase-2 (COX-2) are risk factors for inflammation and cancer of the colon. In the United States, n-6 linolei...
Autores principales: | Romagnolo, Donato F., Donovan, Micah G., Doetschman, Tom C., Selmin, Ornella I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356359/ https://www.ncbi.nlm.nih.gov/pubmed/30650553 http://dx.doi.org/10.3390/nu11010171 |
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