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Are Proteinopathy and Oxidative Stress Two Sides of the Same Coin?

Parkinson’s disease, like other neurodegenerative diseases, exhibits two common features: Proteinopathy and oxidative stress, leading to protein aggregation and mitochondrial damage respectively. Because both protein aggregates and dysfunctional mitochondria are eliminated by autophagy, we suggest t...

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Detalles Bibliográficos
Autores principales: Mehta, Nihar J., Marwah, Praneet Kaur, Njus, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356376/
https://www.ncbi.nlm.nih.gov/pubmed/30654525
http://dx.doi.org/10.3390/cells8010059