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Transfer of Extracellular Vesicle-Associated-RNAs Induces Drug Resistance in ALK-Translocated Lung Adenocarcinoma

Anaplastic lymphoma kinase (ALK) translocation is an actionable mutation in lung adenocarcinoma. Nonetheless tumour consists of heterogeneous cell subpopulations with diverse phenotypes and genotypes, and cancer cells can actively release extracellular vesicles (EVs) to modulate the phenotype of oth...

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Detalles Bibliográficos
Autores principales: Kwok, Hoi-Hin, Ning, Ziyu, Chong, Peony Wing-Chi, Wan, Thomas Shek-Kong, Ng, Margaret Heung-Ling, Ho, Gloria Y.F., Ip, Mary Sau-Man, Lam, David Chi-Leung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356387/
https://www.ncbi.nlm.nih.gov/pubmed/30658414
http://dx.doi.org/10.3390/cancers11010104