Content/Potency Assessment of Botulinum Neurotoxin Type-A by Validated Liquid Chromatography Methods and Bioassays

Botulinum neurotoxin type-A (BoNTA) is one of the seven different serotypes (A to G) produced by Clostridium botulinum. A stability-indicating size-exclusion chromatography (SEC) method was developed and validated, and the specificity was confirmed by forced degradation study, interference of the ex...

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Detalles Bibliográficos
Autores principales: Xavier, Bruna, Perobelli, Rafaela Ferreira, Walter, Maurício Elesbão, da Silva, Francielle Santos, Dalmora, Sérgio Luiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356430/
https://www.ncbi.nlm.nih.gov/pubmed/30642048
http://dx.doi.org/10.3390/toxins11010035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356430/
https://www.ncbi.nlm.nih.gov/pubmed/30642048
http://dx.doi.org/10.3390/toxins11010035

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