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Reading Cancer: Chromatin Readers as Druggable Targets for Cancer Treatment

The epigenetic machinery deputed to control histone post-translational modifications is frequently dysregulated in cancer cells. With epigenetics being naturally reversible, it represents a good target for therapies directed to restore normal gene expression. Since the discovery of Bromodomain and E...

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Detalles Bibliográficos
Autores principales: Mio, Catia, Bulotta, Stefania, Russo, Diego, Damante, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356452/
https://www.ncbi.nlm.nih.gov/pubmed/30634442
http://dx.doi.org/10.3390/cancers11010061