Molecular Networking Reveals Two Distinct Chemotypes in Pyrroloiminoquinone-Producing Tsitsikamma favus Sponges

The temperate marine sponge, Tsitsikamma favus, produces pyrroloiminoquinone alkaloids with potential as anticancer drug leads. We profiled the secondary metabolite reservoir of T. favus sponges using HR-ESI-LC-MS/MS-based molecular networking analysis followed by preparative purification efforts to...

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Detalles Bibliográficos
Autores principales: Kalinski, Jarmo-Charles J., Waterworth, Samantha C., Siwe Noundou, Xavier, Jiwaji, Meesbah, Parker-Nance, Shirley, Krause, Rui W. M., McPhail, Kerry L., Dorrington, Rosemary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356464/
https://www.ncbi.nlm.nih.gov/pubmed/30654589
http://dx.doi.org/10.3390/md17010060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356464/
https://www.ncbi.nlm.nih.gov/pubmed/30654589
http://dx.doi.org/10.3390/md17010060

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