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Bioactivity and Structural Properties of Novel Synthetic Analogues of the Protozoan Toxin Climacostol

Climacostol (5-[(2Z)-non-2-en-1-yl]benzene-1,3-diol) is a resorcinol produced by the protozoan Climacostomum virens for defence against predators. It exerts a potent antimicrobial activity against bacterial and fungal pathogens, inhibits the growth of several human and rodent tumour cells, and is no...

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Detalles Bibliográficos
Autores principales: Buonanno, Federico, Catalani, Elisabetta, Cervia, Davide, Proietti Serafini, Francesca, Picchietti, Simona, Fausto, Anna Maria, Giorgi, Simone, Lupidi, Gabriele, Rossi, Federico Vittorio, Marcantoni, Enrico, Petrelli, Dezemona, Ortenzi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356496/
https://www.ncbi.nlm.nih.gov/pubmed/30650514
http://dx.doi.org/10.3390/toxins11010042