Multiple Parameters Beyond Lipid Binding Affinity Drive Cytotoxicity of Cholesterol-Dependent Cytolysins

The largest superfamily of bacterial virulence factors is pore-forming toxins (PFTs). PFTs are secreted by both pathogenic and non-pathogenic bacteria. PFTs sometimes kill or induce pro-pathogen signaling in mammalian cells, all primarily through plasma membrane perforation, though the parameters th...

Descripción completa

Detalles Bibliográficos
Autores principales: Ray, Sucharit, Thapa, Roshan, Keyel, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356533/
https://www.ncbi.nlm.nih.gov/pubmed/30577571
http://dx.doi.org/10.3390/toxins11010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356533/
https://www.ncbi.nlm.nih.gov/pubmed/30577571
http://dx.doi.org/10.3390/toxins11010001

Ejemplares similares