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HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells

The hypoxia-inducible transcription factors (HIF)-1/2α are the main oxygen sensors which regulate the adaptation to intratumoral hypoxia. The aim of this study was to assess the role of the HIF proteins in regulating the radiation response of a non-small cell lung cancer (NSCLC) in vitro model. To d...

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Detalles Bibliográficos
Autores principales: Moreno Roig, Eloy, Groot, Arjan J., Yaromina, Ala, Hendrickx, Tessa C., Barbeau, Lydie M. O., Giuranno, Lorena, Dams, Glenn, Ient, Jonathan, Olivo Pimentel, Veronica, van Gisbergen, Marike W., Dubois, Ludwig J., Vooijs, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356534/
https://www.ncbi.nlm.nih.gov/pubmed/30642030
http://dx.doi.org/10.3390/cells8010045