A Human ABC Transporter ABCC4 Gene SNP (rs11568658, 559 G > T, G187W) Reduces ABCC4-Dependent Drug Resistance

Broad-spectrum drug resistance is a major obstacle in cancer treatment, which is often caused by overexpression of ABC transporters the levels of which vary between individuals due to single-nucleotide polymorphisms (SNPs) in their genes. In the present study, we focused on the human ABC transporter...

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Detalles Bibliográficos
Autores principales: Tsukamoto, Megumi, Yamashita, Miho, Nishi, Tsuyoshi, Nakagawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356542/
https://www.ncbi.nlm.nih.gov/pubmed/30634695
http://dx.doi.org/10.3390/cells8010039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356542/
https://www.ncbi.nlm.nih.gov/pubmed/30634695
http://dx.doi.org/10.3390/cells8010039

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