Oxymatrine Attenuates Tumor Growth and Deactivates STAT5 Signaling in a Lung Cancer Xenograft Model

Oxymatrine (OMT) is a major alkaloid found in radix Sophorae flavescentis extract and has been reported to exhibit various pharmacological activities. We elucidated the detailed molecular mechanism(s) underlying the therapeutic actions of OMT in non-small cell lung cancer (NSCLC) cells and a xenogra...

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Detalles Bibliográficos
Autores principales: Jung, Young Yun, Shanmugam, Muthu K., Narula, Acharan S., Kim, Chulwon, Lee, Jong Hyun, Namjoshi, Ojas A., Blough, Bruce E., Sethi, Gautam, Ahn, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356594/
https://www.ncbi.nlm.nih.gov/pubmed/30621055
http://dx.doi.org/10.3390/cancers11010049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356594/
https://www.ncbi.nlm.nih.gov/pubmed/30621055
http://dx.doi.org/10.3390/cancers11010049

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