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Oxymatrine Attenuates Tumor Growth and Deactivates STAT5 Signaling in a Lung Cancer Xenograft Model
Oxymatrine (OMT) is a major alkaloid found in radix Sophorae flavescentis extract and has been reported to exhibit various pharmacological activities. We elucidated the detailed molecular mechanism(s) underlying the therapeutic actions of OMT in non-small cell lung cancer (NSCLC) cells and a xenogra...
Autores principales: | Jung, Young Yun, Shanmugam, Muthu K., Narula, Acharan S., Kim, Chulwon, Lee, Jong Hyun, Namjoshi, Ojas A., Blough, Bruce E., Sethi, Gautam, Ahn, Kwang Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356594/ https://www.ncbi.nlm.nih.gov/pubmed/30621055 http://dx.doi.org/10.3390/cancers11010049 |
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