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Methylation Status of the Adeno-Associated Virus Type 2 (AAV2)

To analyze the methylation status of wild-type adeno-associated virus type 2 (AAV2), bisulfite PCR sequencing (BPS) of the packaged viral genome and its integrated form was performed and 262 of the total 266 CG dinucleotides (CpG) were mapped. In virion-packaged DNA, the ratio of the methylated cyto...

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Detalles Bibliográficos
Autores principales: Tóth, Renáta, Mészáros, István, Hüser, Daniela, Forró, Barbara, Marton, Szilvia, Olasz, Ferenc, Bányai, Krisztián, Heilbronn, Regine, Zádori, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356613/
https://www.ncbi.nlm.nih.gov/pubmed/30634383
http://dx.doi.org/10.3390/v11010038