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Jumonji C Demethylases in Cellular Senescence

Senescence is a stable cell cycle arrest that is either tumor suppressive or tumor promoting depending on context. Epigenetic changes such as histone methylation are known to affect both the induction and suppression of senescence by altering expression of genes that regulate the cell cycle and the...

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Detalles Bibliográficos
Autores principales: Leon, Kelly E., Aird, Katherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356615/
https://www.ncbi.nlm.nih.gov/pubmed/30634491
http://dx.doi.org/10.3390/genes10010033