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Increasing the TRPM2 Channel Expression in Human Neuroblastoma SH-SY5Y Cells Augments the Susceptibility to ROS-Induced Cell Death

Human neuroblastoma SH-SY5Y cells are a widely-used human neuronal cell model in the study of neurodegeneration. A recent study shows that, 1-methyl-4-phenylpyridine ion (MPP), which selectively causes dopaminergic neuronal death leading to Parkinson’s disease-like symptoms, can reduce SH-SY5Y cell...

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Detalles Bibliográficos
Autores principales: An, Xinfang, Fu, Zixing, Mai, Chendi, Wang, Weiming, Wei, Linyu, Li, Dongliang, Li, Chaokun, Jiang, Lin-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356620/
https://www.ncbi.nlm.nih.gov/pubmed/30625984
http://dx.doi.org/10.3390/cells8010028