The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells

Ranking among the most lethal tumour entities, pancreatic duct adenocarcinoma cells invade neighbouring tissue resulting in high incidence of metastasis. They are supported by tumour stroma fibroblasts which have undergone differentiation into cancer-associated fibroblasts (CAFs). Stiffness of cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Martins Cavaco, Ana C., Rezaei, Maryam, Caliandro, Michele F., Martins Lima, Augusto, Stehling, Martin, Dhayat, Sameer A., Haier, Jörg, Brakebusch, Cord, Eble, Johannes A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356648/
https://www.ncbi.nlm.nih.gov/pubmed/30583482
http://dx.doi.org/10.3390/cancers11010014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356648/
https://www.ncbi.nlm.nih.gov/pubmed/30583482
http://dx.doi.org/10.3390/cancers11010014

Ejemplares similares