Cargando…

The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells

Ranking among the most lethal tumour entities, pancreatic duct adenocarcinoma cells invade neighbouring tissue resulting in high incidence of metastasis. They are supported by tumour stroma fibroblasts which have undergone differentiation into cancer-associated fibroblasts (CAFs). Stiffness of cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martins Cavaco, Ana C., Rezaei, Maryam, Caliandro, Michele F., Martins Lima, Augusto, Stehling, Martin, Dhayat, Sameer A., Haier, Jörg, Brakebusch, Cord, Eble, Johannes A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356648/ https://www.ncbi.nlm.nih.gov/pubmed/30583482 http://dx.doi.org/10.3390/cancers11010014

Ejemplares similares

Autoimmunity against laminin 332
por: Patzelt, Sabrina, et al.
Publicado: (2023)

Laminin 332 processing impacts cellular behavior
por: Rousselle, Patricia, et al.
Publicado: (2013)

Anti-Laminin 332-Type Mucous Membrane Pemphigoid
por: Shi, Luhuai, et al.
Publicado: (2022)

Migration of breast cancer cell lines in response to pulmonary laminin 332
por: Carpenter, Philip M., et al.
Publicado: (2016)

Molecular diagnosis of anti-laminin 332 (epiligrin) mucous membrane pemphigoid
por: Chiorean, Roxana, et al.
Publicado: (2018)

Laminin 511 partners with laminin 332 to mediate directional migration of Madin–Darby canine kidney epithelial cells
por: Greciano, Patricia G., et al.
Publicado: (2012)

Comparison of Two Diagnostic Assays for Anti-Laminin 332 Mucous Membrane Pemphigoid
por: Goletz, Stephanie, et al.
Publicado: (2021)

Extracellular Vesicle Transfer from Endothelial Cells Drives VE-Cadherin Expression in Breast Cancer Cells, Thereby Causing Heterotypic Cell Contacts
por: Rezaei, Maryam, et al.
Publicado: (2020)

Expression of the gamma 2 chain of laminin-332 in eutopic and ectopic endometrium of patients with endometriosis
por: Locci, Rosella, et al.
Publicado: (2013)

Invasive breast cancer induces laminin-332 upregulation and integrin β4 neoexpression in myofibroblasts to confer an anoikis-resistant phenotype during tissue remodeling
por: Kim, Baek Gil, et al.
Publicado: (2012)

Integrin Regulation of CAF Differentiation and Function
por: DiPersio, C. Michael, et al.
Publicado: (2019)

Polymerized Laminin-332 Matrix Supports Rapid and Tight Adhesion of Keratinocytes, Suppressing Cell Migration
por: Kariya, Yoshinobu, et al.
Publicado: (2012)

Lysophosphatidic Acid Upregulates Laminin-332 Expression during A431 Cell Colony Dispersal
por: Yamashita, Hironobu, et al.
Publicado: (2010)

Subunit-Specific Reactivity of Autoantibodies Against Laminin-332 Reveals Direct Inflammatory Mechanisms on Keratinocytes
por: Bao, Lei, et al.
Publicado: (2021)

Gene Expression in Amnion-Derived Cells Cultured on Recombinant Laminin 332—A Preliminary Study
por: Skowron-Kandzia, Katarzyna, et al.
Publicado: (2021)

Laminin-332 γ2 Monomeric Chain Promotes Adhesion and Migration of Hepatocellular Carcinoma Cells
por: Scialpi, Rosanna, et al.
Publicado: (2023)

Laminin 332 expression levels predict clinical outcomes and chemotherapy response in patients with pancreatic adenocarcinoma
por: Sari, Bilge, et al.
Publicado: (2023)

Dysregulation of miRNA Expression in Cancer Associated Fibroblasts (CAFs) and Its Consequences on the Tumor Microenvironment
por: Schoepp, Maren, et al.
Publicado: (2017)

Divergent mechanisms underlie Smad4-mediated positive regulation of the three genes encoding the basement membrane component laminin-332 (laminin-5)
por: Zboralski, Dirk, et al.
Publicado: (2008)

Invasion-Associated Reorganization of Laminin 332 in Oral Squamous Cell Carcinomas: The Role of the Laminin γ2 Chain in Tumor Biology, Diagnosis, and Therapy
por: Berndt, Alexander, et al.
Publicado: (2022)

Laminin-332 promotes the invasion of oesophageal squamous cell carcinoma via PI3K activation
por: Baba, Y, et al.
Publicado: (2008)

Multiple Skin Squamous Cell Carcinomas in Junctional Epidermolysis Bullosa Due to Altered Laminin-332 Function
por: Fortugno, Paola, et al.
Publicado: (2020)

Gentamicin Induces Laminin 332 and Improves Wound Healing in Junctional Epidermolysis Bullosa Patients with Nonsense Mutations
por: Kwong, Andrew, et al.
Publicado: (2020)

Laminin-332 mediates proliferation, apoptosis, invasion, migration and epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma
por: Huang, Caiqun, et al.
Publicado: (2021)

Complexity of Transcriptional and Translational Interference of Laminin-332 Subunits in Junctional Epidermolysis Bullosa with LAMB3 Mutations
por: HOU, Ping-Chen, et al.
Publicado: (2021)

Integrins, CAFs and Mechanical Forces in the Progression of Cancer
por: Jang, Imjoo, et al.
Publicado: (2019)

Overexpression of β3 Chains of Laminin-332 is Associated With Clinicopathologic Features and Decreased Survival in Patients With Pancreatic Adenocarcinoma
por: Chen, Jun, et al.
Publicado: (2015)

Case report: A case of anti-laminin 332 mucous membrane pemphigoid associated with severe pharyngolaryngeal involvement
por: Quattri, Eleonora, et al.
Publicado: (2022)

MicroRNA-100 and microRNA-21 as markers of survival and chemotherapy response in pancreatic ductal adenocarcinoma UICC stage II
por: Dhayat, Sameer Abdallah, et al.
Publicado: (2015)

Structural mechanism of laminin recognition by integrin
por: Arimori, Takao, et al.
Publicado: (2021)

Laminin-332 alters connexin profile, dye coupling and intercellular Ca(2+ )waves in ciliated tracheal epithelial cells
por: Isakson, Brant E, et al.
Publicado: (2006)

Corrigendum: Case report: A case of anti-laminin 332 mucous membrane pemphigoid associated with severe pharyngolaryngeal involvement
por: Quattri, Eleonora, et al.
Publicado: (2022)

Genetic analysis of β1 integrin “activation motifs” in mice
por: Czuchra, Aleksandra, et al.
Publicado: (2006)

Autocrine Transforming Growth Factor-β1 Activation Mediated by Integrin αVβ3 Regulates Transcriptional Expression of Laminin-332 in Madin-Darby Canine Kidney Epithelial Cells
por: Moyano, Jose V., et al.
Publicado: (2010)

Circulating microRNA-200 Family as Diagnostic Marker in Hepatocellular Carcinoma
por: Dhayat, Sameer A., et al.
Publicado: (2015)

Immunohistochemical Study of Laminin-332 γ2 Chain and MMP-9 in High Risk of Malignant Transformation Oral Lesions and OSCC
por: Silva, Eline Manhães Reid, et al.
Publicado: (2018)

Overexpression of α3, β3 and γ2 chains of laminin-332 is associated with poor prognosis in pancreatic ductal adenocarcinoma
por: Chen, Jun, et al.
Publicado: (2018)

Increased Fibrosis in a Mouse Model of Anti-Laminin 332 Mucous Membrane Pemphigoid Remains Unaltered by Inhibition of Aldehyde Dehydrogenase
por: Patzelt, Sabrina, et al.
Publicado: (2022)

Laminin 332-functionalized coating to regulate the behavior of keratinocytes and gingival mesenchymal stem cells to enhance implant soft tissue sealing
por: Liu, Lipeng, et al.
Publicado: (2022)

Human neutrophil adherence to laminin in vitro. Evidence for a distinct neutrophil integrin receptor for laminin
Publicado: (1990)

Cannot write session to /tmp/vufind_sessions/sess_n8vhoqnn029uov5dcf6fjnj88d