Combining a Fusion Inhibitory Peptide Targeting the MERS-CoV S2 Protein HR1 Domain and a Neutralizing Antibody Specific for the S1 Protein Receptor-Binding Domain (RBD) Showed Potent Synergism against Pseudotyped MERS-CoV with or without Mutations in RBD

Middle East respiratory syndrome coronavirus (MERS-CoV) has continuously posed a threat to public health worldwide, yet no therapeutics or vaccines are currently available to prevent or treat MERS-CoV infection. We previously identified a fusion inhibitory peptide (HR2P-M2) targeting the MERS-CoV S2...

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Detalles Bibliográficos
Autores principales: Wang, Cong, Hua, Chen, Xia, Shuai, Li, Weihua, Lu, Lu, Jiang, Shibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356712/
https://www.ncbi.nlm.nih.gov/pubmed/30621343
http://dx.doi.org/10.3390/v11010031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356712/
https://www.ncbi.nlm.nih.gov/pubmed/30621343
http://dx.doi.org/10.3390/v11010031

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