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Uncovering Flavivirus Host Dependency Factors through a Genome-Wide Gain-of-Function Screen

Flaviviruses, such as dengue (DENV), West Nile (WNV), yellow fever (YFV) and Zika (ZIKV) viruses, are mosquito-borne pathogens that present a major risk to global public health. To identify host factors that promote flavivirus replication, we performed a genome-wide gain-of-function cDNA screen for...

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Detalles Bibliográficos
Autores principales: Petrova, Evgeniya, Gracias, Ségolène, Beauclair, Guillaume, Tangy, Frédéric, Jouvenet, Nolwenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356745/
https://www.ncbi.nlm.nih.gov/pubmed/30650657
http://dx.doi.org/10.3390/v11010068