A DNA Vaccine Encoding SA-4-1BBL Fused to HPV-16 E7 Antigen Has Prophylactic and Therapeutic Efficacy in a Cervical Cancer Mouse Model

The SA-4-1BBL, an oligomeric novel form of the natural ligand for the 4-1BB co-stimulatory receptor of the tumor necrosis factor (TNF) superfamily, as a recombinant protein has potent pleiotropic effects on cells of innate, adaptive, and regulatory immunity with demonstrated therapeutic efficacy in...

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Detalles Bibliográficos
Autores principales: Garza-Morales, Rodolfo, Perez-Trujillo, Jose J., Martinez-Jaramillo, Elvis, Saucedo-Cardenas, Odila, Loera-Arias, Maria J., Garcia-Garcia, Aracely, Rodriguez-Rocha, Humberto, Yolcu, Esma, Shirwan, Haval, Gomez-Gutierrez, Jorge G., Montes-de-Oca-Luna, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356763/
https://www.ncbi.nlm.nih.gov/pubmed/30650588
http://dx.doi.org/10.3390/cancers11010096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356763/
https://www.ncbi.nlm.nih.gov/pubmed/30650588
http://dx.doi.org/10.3390/cancers11010096

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