Novel STAT3 Inhibitor LDOC1 Targets Phospho-JAK2 for Degradation by Interacting with LNX1 and Regulates the Aggressiveness of Lung Cancer

Meta-analysis revealed that Leucine Zipper Down-Regulated In Cancer 1 (LDOC1) increased methylation more in people with lung tumors than in those who were healthy and never smoked. Quantitative methylation-specific PCR revealed that cigarette smoke condensate (CSC) exposure drives LDOC1 promoter hyp...

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Detalles Bibliográficos
Autores principales: Lee, Chia-Huei, Yang, Ji-Rui, Chen, Chih-Yu, Tsai, Ming-Hsien, Hung, Pin-Feng, Chen, Shin-Jih, Chiang, Shang-Lun, Chang, Han, Lin, Pinpin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356782/
https://www.ncbi.nlm.nih.gov/pubmed/30634502
http://dx.doi.org/10.3390/cancers11010063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356782/
https://www.ncbi.nlm.nih.gov/pubmed/30634502
http://dx.doi.org/10.3390/cancers11010063

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