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Role of FoxO Proteins in Cellular Response to Antitumor Agents

FoxO proteins (FoxOs) are transcription factors with a common DNA binding domain that confers selectivity for DNA interaction. In human cells, four proteins (FoxO1, FoxO3, FoxO4 and FoxO6), with redundant activity, exhibit mainly a positive effect on genes involved in cell cycle, apoptosis regulatio...

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Detalles Bibliográficos
Autores principales: Beretta, Giovanni Luca, Corno, Cristina, Zaffaroni, Nadia, Perego, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356788/
https://www.ncbi.nlm.nih.gov/pubmed/30646603
http://dx.doi.org/10.3390/cancers11010090