On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation

The DNA damage response (DDR) is a designation for a number of pathways that protects our DNA from various damaging agents. In normal cells, the DDR is extremely important for maintaining genome integrity, but in cancer cells these mechanisms counteract therapy-induced DNA damage. Inhibition of the...

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Detalles Bibliográficos
Autores principales: van den Tempel, Nathalie, Zelensky, Alex N., Odijk, Hanny, Laffeber, Charlie, Schmidt, Christine K., Brandsma, Inger, Demmers, Jeroen, Krawczyk, Przemek M., Kanaar, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356811/
https://www.ncbi.nlm.nih.gov/pubmed/30650591
http://dx.doi.org/10.3390/cancers11010097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356811/
https://www.ncbi.nlm.nih.gov/pubmed/30650591
http://dx.doi.org/10.3390/cancers11010097

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