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The Microtubule-Associated Innate Immune Sensor GEF-H1 Does Not Influence Mouse Norovirus Replication in Murine Macrophages

Norovirus is an acute infection of the gastrointestinal tract causing rapid induction of vomiting and diarrhoea. The infection is sensed and controlled by the innate immune system, particularly by the RNA helicase MDA-5 and type I and III interferons (IFNs). We have observed that intracellular repli...

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Detalles Bibliográficos
Autores principales: Fritzlar, Svenja, White, Peter A., Mackenzie, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356845/
https://www.ncbi.nlm.nih.gov/pubmed/30634661
http://dx.doi.org/10.3390/v11010047