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Tsuji–Trost Cyclization of Disulfonamides: Synthesis of 12-Membered, 11-Membered, and Pyridine-Fused Macrocyclic Triamines

[Image: see text] Macrocyclic triamine disulfonamides can be synthesized by double Tsuji–Trost N-allylation reaction of open-chain disulfonamides with 2-alkylidene-1,3-propanediyl bis(carbonates). The previously used Atkins–Richman macrocyclization method generally gives lower yields and requires mo...

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Detalles Bibliográficos
Autores principales: Ali, Rameez, Anugu, Sreenivasa, Chawla, Reena, Demillo, Violeta G., Goulinet-Mateo, Florian, Gyawali, Sagar, Hamal, Sunil, Jones, Dylan E., Lamprecht, Katrin, Le, Truc, Lumangtad, Liezel A., Pflug, Nicholas C., Sama, Alekhya, Scarbrough, Emily D., Bell, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356871/
https://www.ncbi.nlm.nih.gov/pubmed/30729225
http://dx.doi.org/10.1021/acsomega.8b02555