Comparative Behavioral Phenotypes of Fmr1 KO, Fxr2 Het, and Fmr1 KO/Fxr2 Het Mice

Fragile X syndrome (FXS) is caused by silencing of the FMR1 gene leading to loss of the protein product fragile X mental retardation protein (FMRP). FXS is the most common monogenic cause of intellectual disability. There are two known mammalian paralogs of FMRP, FXR1P, and FXR2P. The functions of F...

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Detalles Bibliográficos
Autores principales: Saré, Rachel Michelle, Figueroa, Christopher, Lemons, Abigail, Loutaev, Inna, Beebe Smith, Carolyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356887/
https://www.ncbi.nlm.nih.gov/pubmed/30654445
http://dx.doi.org/10.3390/brainsci9010013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356887/
https://www.ncbi.nlm.nih.gov/pubmed/30654445
http://dx.doi.org/10.3390/brainsci9010013

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