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Endolysosomal Ca(2+) Signalling and Cancer Hallmarks: Two-Pore Channels on the Move, TRPML1 Lags Behind!

The acidic vesicles of the endolysosomal (EL) system are emerging as an intracellular Ca(2+) store implicated in the regulation of multiple cellular functions. The EL Ca(2+) store releases Ca(2+) through a variety of Ca(2+)-permeable channels, including Transient Receptor Potential (TRP) Mucolipin 1...

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Detalles Bibliográficos
Autores principales: Faris, Pawan, Shekha, Mudhir, Montagna, Daniela, Guerra, Germano, Moccia, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356888/
https://www.ncbi.nlm.nih.gov/pubmed/30591696
http://dx.doi.org/10.3390/cancers11010027