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PKA at a Cross-Road of Signaling Pathways Involved in the Regulation of Glioblastoma Migration and Invasion by the Neuropeptides VIP and PACAP

Glioblastoma (GBM) remains an incurable disease, mainly due to the high migration and invasion potency of GBM cells inside the brain. PI3K/Akt, Sonic Hedgehog (SHH), and PKA pathways play major regulatory roles in the progression of GBM. The vasoactive intestinal peptide (VIP) family of neuropeptide...

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Detalles Bibliográficos
Autores principales: Bensalma, Souheyla, Turpault, Soumaya, Balandre, Annie-Claire, De Boisvilliers, Madryssa, Gaillard, Afsaneh, Chadéneau, Corinne, Muller, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356933/
https://www.ncbi.nlm.nih.gov/pubmed/30669581
http://dx.doi.org/10.3390/cancers11010123