Structural Insights into Phylloquinone (Vitamin K1), Menaquinone (MK4, MK7), and Menadione (Vitamin K3) Binding to VKORC1

Vitamin K family molecules—phylloquinone (K1), menaquinone (K2), and menadione (K3)—act as γ-glutamyl carboxylase (GGCX)-exclusive cofactors in their hydroquinone state, activating proteins of main importance for blood coagulation in the liver and for arterial calcification prevention and energy met...

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Detalles Bibliográficos
Autores principales: Chatron, Nolan, Hammed, Abdessalem, Benoît, Etienne, Lattard, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357001/
https://www.ncbi.nlm.nih.gov/pubmed/30609653
http://dx.doi.org/10.3390/nu11010067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357001/
https://www.ncbi.nlm.nih.gov/pubmed/30609653
http://dx.doi.org/10.3390/nu11010067

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