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Intradermal Application of Crotamine Induces Inflammatory and Immunological Changes In Vivo

Crotamine is a single-chain polypeptide with cell-penetrating properties, which is considered a promising molecule for clinical use. Nevertheless, its biosafety data are still scarce. Herein, we assessed the in vivo proinflammatory properties of crotamine, including its local effect and systemic ser...

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Detalles Bibliográficos
Autores principales: Silvestrini, Ana Vitória Pupo, de Macedo, Luana Henrique, de Andrade, Thiago Antônio Moretti, Mendes, Maíra Felonato, Pigoso, Acácio Antônio, Mazzi, Maurício Ventura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357061/
https://www.ncbi.nlm.nih.gov/pubmed/30646542
http://dx.doi.org/10.3390/toxins11010039