Stimulation of Replication Template-Switching by DNA-Protein Crosslinks

Covalent DNA protein crosslinks (DPCs) are common lesions that block replication. We examine here the consequence of DPCs on mutagenesis involving replicational template-switch reactions in Escherichia coli. 5-Azacytidine (5-azaC) is a potent mutagen for template-switching. This effect is dependent...

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Detalles Bibliográficos
Autores principales: Laranjo, Laura T., Klaric, Julie A., Pearlman, Leah R., Lovett, Susan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357072/
https://www.ncbi.nlm.nih.gov/pubmed/30591691
http://dx.doi.org/10.3390/genes10010014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357072/
https://www.ncbi.nlm.nih.gov/pubmed/30591691
http://dx.doi.org/10.3390/genes10010014

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