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Stimulation of Replication Template-Switching by DNA-Protein Crosslinks
Covalent DNA protein crosslinks (DPCs) are common lesions that block replication. We examine here the consequence of DPCs on mutagenesis involving replicational template-switch reactions in Escherichia coli. 5-Azacytidine (5-azaC) is a potent mutagen for template-switching. This effect is dependent...
Autores principales: | Laranjo, Laura T., Klaric, Julie A., Pearlman, Leah R., Lovett, Susan T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357072/ https://www.ncbi.nlm.nih.gov/pubmed/30591691 http://dx.doi.org/10.3390/genes10010014 |
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