Functional Comparison of XPF Missense Mutations Associated to Multiple DNA Repair Disorders

XPF endonuclease is one of the most important DNA repair proteins. Encoded by XPF/ERCC4, XPF provides the enzymatic activity of XPF-ERCC1 heterodimer, an endonuclease that incises at the 5’ side of various DNA lesions. XPF is essential for nucleotide excision repair (NER) and interstrand crosslink r...

Descripción completa

Detalles Bibliográficos
Autores principales: Marín, Maria, Ramírez, María José, Aza Carmona, Miriam, Jia, Nan, Ogi, Tomoo, Bogliolo, Massimo, Surrallés, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357085/
https://www.ncbi.nlm.nih.gov/pubmed/30658521
http://dx.doi.org/10.3390/genes10010060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357085/
https://www.ncbi.nlm.nih.gov/pubmed/30658521
http://dx.doi.org/10.3390/genes10010060

Ejemplares similares