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Functional Comparison of XPF Missense Mutations Associated to Multiple DNA Repair Disorders

XPF endonuclease is one of the most important DNA repair proteins. Encoded by XPF/ERCC4, XPF provides the enzymatic activity of XPF-ERCC1 heterodimer, an endonuclease that incises at the 5’ side of various DNA lesions. XPF is essential for nucleotide excision repair (NER) and interstrand crosslink r...

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Detalles Bibliográficos
Autores principales:	Marín, Maria, Ramírez, María José, Aza Carmona, Miriam, Jia, Nan, Ogi, Tomoo, Bogliolo, Massimo, Surrallés, Jordi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357085/ https://www.ncbi.nlm.nih.gov/pubmed/30658521 http://dx.doi.org/10.3390/genes10010060

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